| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4824242 | B | Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate by spectrophotometric assay | Leishmania infantum | 29 | assay format | Scientific Literature | ||
| 2. | ALA4824244 | B | Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR dimer using TS2 as substrate after 16 hrs by ELISA | Leishmania infantum | 27 | assay format | Scientific Literature | ||
| 3. | ALA4824246 | B | Inhibition of recombinant human GR oxidoreductase activity by DTNB-reagent based spectrophotometric method | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 4. | ALA4824258 | B | Inhibition of Trypanosoma brucei TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assay | Trypanosoma brucei | 7 | single protein format | Scientific Literature | ||
| 5. | ALA4824259 | B | Inhibition of Trypanosoma congolense TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assay | Trypanosoma congolense | 7 | assay format | Scientific Literature | ||
| 6. | ALA4824261 | F | Antileishmanial activity against promastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells incubated for 24 hrs by propidium iodide staining based flow cytometry | Leishmania infantum | 23 | organism-based format | Scientific Literature | ||
| 7. | ALA4824262 | F | Antileishmanial activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells incubated for 24 hrs by propidium iodide staining based flow cytometry | Leishmania infantum | 23 | organism-based format | Scientific Literature | ||
| 8. | ALA4824263 | A | Cytotoxicity against human HepG2 cells incubated for 24 hrs by crystal violet staining based assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 9. | ALA4824264 | T | Selectivity index, ratio of EC50 for human HepG2 cells to EC50 for promastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells | 23 | cell-based format | Scientific Literature | |||
| 10. | ALA4824265 | T | Selectivity index, ratio of EC50 for human HepG2 cells to EC50 for axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells | 23 | cell-based format | Scientific Literature |
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