| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4838342 | B | Substrate activity at recombinant human NQO1 assessed as catalytic efficiency preincubated for 3 mins followed by NADPH addition and measured at 2 sec interval for 5 mins | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA4838343 | B | Substrate activity at recombinant human NQO1 assessed as enzymatic reduction rate at 10 uM | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 3. | ALA4838344 | F | Cytotoxicity against human A549 cells overexpressing NQO1 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 4. | ALA4838346 | P | Intrinsic solubility of the compound after 8 hrs by potentiometric titration method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4838347 | P | Solubility of the compound in pH 3 after 8 hrs by potentiometric titration method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4838348 | P | Lipophilicity, logD of the compound at pH 7.4 by potentiometric titration method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4838349 | A | Cytotoxicity against NQO1-deficient human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 8. | ALA4838350 | U | Selectivity index, ratio of IC50 for NQO1-deficient human L02 cells to IC50 for human A549 cells overexpressing NQO1 incubated for 72 hrs by MTT assay | 16 | assay format | Scientific Literature |
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