# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4812316 | B | Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
2. | ALA4812317 | B | Inhibition of C-terminal hexaHis-tagged TPO (unknown origin) expressed in Trichoplusia ni insect cells using 3-iodo tyrosine as substrate preincubated for 10 mins followed by substrate and H2O2 addition and further incubated for 15 mins | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA4812318 | A | Time dependent inhibition of CYP3A4 (unknown origin) measured at 30 mins | Homo sapiens | 14 | single protein format | Scientific Literature | ||
4. | ALA4812320 | A | Ratio of IC50 for time dependent inhibition of CYP3A4 (unknown origin) measured at 30 mins to IC50 for time dependent inhibition of CYP3A4 (unknown origin) measured at 5 mins | Homo sapiens | 14 | single protein format | Scientific Literature | ||
5. | ALA4812321 | A | Protein binding in human plasma | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
6. | ALA4812322 | A | Half life in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
7. | ALA4812323 | A | Half life in mouse at 1 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA4812324 | A | Volume of distribution at steady state in mouse at 1 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA4812325 | A | Clearance in mouse at 1 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA4812326 | A | Permeability of the compound by PAMPA method | 1 | assay format | Scientific Literature | |||
11. | ALA4812327 | B | Inhibition of PMA-induced MPO in human Neutrophil incubated for 3 mins by luminometry | Homo sapiens | 2 | tissue-based format | Scientific Literature |