# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4804287 | F | Induction of apoptosis in human MM1.S cells assessed as live cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 90.07 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
2. | ALA4804288 | F | Induction of apoptosis in human MM1.S cells assessed as early apoptotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 7.65 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
3. | ALA4804289 | F | Induction of apoptosis in human MM1.S cells assessed as late apoptotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 2.09 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
4. | ALA4804290 | F | Induction of apoptosis in human MM1.S cells assessed as necrotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 0.19 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
5. | ALA4804291 | F | Induction of apoptosis in human NCI-H929 cells assessed as live cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 89.21 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
6. | ALA4804292 | F | Induction of apoptosis in human NCI-H929 cells assessed as early apoptotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 5.48 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
7. | ALA4804293 | F | Induction of apoptosis in human NCI-H929 cells assessed as late apoptotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 4.24 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
8. | ALA4804294 | F | Induction of apoptosis in human NCI-H929 cells assessed as necrotic cells measured after 48 hrs by annevxinV/FITC-propidium iodide staining based flow cytometry (Rvb = 1.07 %) | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
9. | ALA4804295 | F | Upregulation of YAP1 protein level in human NCI-H929 cells at 1 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
10. | ALA4804296 | F | Upregulation of PUMA protein level in human NCI-H929 cells at 1 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
11. | ALA4804297 | F | Upregulation of BAX protein level in human NCI-H929 cells at 1 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
12. | ALA4804298 | F | Upregulation of p21 protein level in human NCI-H929 cells at 1 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
13. | ALA4804299 | F | Induction of apoptosis in human NCI-H929 cells assessed as induction of PARP cleavage at 1 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
14. | ALA4804302 | F | Upregulation of YAP1 protein level in human NCI-H929 cells at 3 to 10 uM measured after 72 hrs by Western blot analysis | Homo sapiens | 2 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
15. | ALA4804303 | F | Upregulation of YAP1 protein level in human MM1.S cells at 3 to 10 uM measured after 72 hrs by Western blot analysis | Homo sapiens | 2 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
16. | ALA4804304 | F | Upregulation of YAP1 protein level in human MM1.S cells at 1 uM measured after 16 hrs by Western blot analysis | Homo sapiens | 5 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
17. | ALA4804305 | F | Downregulation of phosphorylated-MOB1 protein level in human MM1.S cells at 1 to 10 uM measured after 6 hrs by Western blot analysis | Homo sapiens | 7 | ALA4804281 | cell-based format | Patent Bioactivity Data | |
18. | ALA4804306 | B | Inhibition of STK4 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 59 | ALA4804281 | single protein format | Patent Bioactivity Data | |
19. | ALA4804308 | B | Inhibition of STK3 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 11 | ALA4804281 | single protein format | Patent Bioactivity Data | |
20. | ALA4804309 | B | Inhibition of STK24 (unknown origin) using fluorescein-labelled Ser/Thr-07 peptide as substrate incubated for 1 hr in presence of ATP at Km concentration by Z-LYTE assay | Homo sapiens | 12 | ALA4804281 | single protein format | Patent Bioactivity Data |