# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4808365 | B | Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cells incubated for 120 mins by radiometric scintillation analysis | Homo sapiens | 12 | ALA4808166 | cell-based format | Scientific Literature | |
2. | ALA4834768 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 2.5 ng/ml measured on the bench-top for 2 hrs by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
3. | ALA4834770 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 160 ng/ml measured on the bench-top for 2 hrs by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
4. | ALA4834771 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 2.5 ng/ml measured in autosampler for 24 hrs by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
5. | ALA4834772 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 160 ng/ml measured in autosampler for 24 hrs by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
6. | ALA4834773 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 2.5 ng/ml measured under freeze-thaw conditions for 3 cycles by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
7. | ALA4834774 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 160 ng/ml measured under freeze-thaw conditions for 3 cycles by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
8. | ALA4834775 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 2.5 ng/ml measured at -80 degC for 4 weeks by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
9. | ALA4834776 | A | Stability of the compound in rat plasma assessed as proportion of compound deviation from nominal concentration at 160 ng/ml measured at -80 degC for 4 weeks by UPLC-MS analysis | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
10. | ALA4834818 | A | Tmax in Sprague-Dawley rat plasma at 0.79 mg/kg, po administered as LKT formulation measured for 24 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
11. | ALA4834819 | A | Cmax in Sprague-Dawley rat plasma at 0.79 mg/kg, po administered as LKT formulation measured for 24 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
12. | ALA4834820 | A | Tmax in Sprague-Dawley rat plasma at 1.23 mg/kg, po administered as OPMS liquid formulation measured for 24 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
13. | ALA4834821 | A | Cmax in Sprague-Dawley rat plasma at 1.23 mg/kg, po administered as OPMS liquid formulation measured for 24 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
14. | ALA4834826 | A | Drug uptake in Sprague-Dawley rat plasma at at 0.79 mg/kg, po administered as LKT formulation measured within 1 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
15. | ALA4834827 | A | Drug uptake in Sprague-Dawley rat plasma at 1.23 mg/kg, po administered as OPMS liquid formulation measured within 1 hrs by UPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4834399 | organism-based format | Scientific Literature | |
16. | ALA4834834 | A | Stability of the compound in rat plasma assessed as drug recovery | Rattus norvegicus | 11 | ALA4834399 | cell-free format | Scientific Literature | |
17. | ALA4834835 | P | Stability of the compound in water-methanol mixture (1:1) assessed as drug recovery | 11 | ALA4834399 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA5054001 | A | Elimination rate constant in Sprague-Dawley rat at 1.25 mg/kg, iv | Rattus norvegicus | 1 | ALA5053503 | organism-based format | Scientific Literature | |
19. | ALA5054002 | A | Apparent volume of distributed in Sprague-Dawley rat at 1.25 mg/kg, iv | Rattus norvegicus | 1 | ALA5053503 | organism-based format | Scientific Literature | |
20. | ALA5054003 | A | AUCinfinity in Sprague-Dawley rat at 1.25 mg/kg, iv | Rattus norvegicus | 1 | ALA5053503 | organism-based format | Scientific Literature |