| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835944 | B | Displacement of [125I]CGRP from human CGRP receptor in human SK-N-MC cells measured after 2 hrs by scintillation counting analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA4835945 | A | Microsomal stability in human liver microsomes assessed as parent compound remaining at 0.5 M measured after 10 mins | Homo sapiens | 15 | microsome format | Scientific Literature | ||
| 3. | ALA4835946 | A | Microsomal stability in rat microsomes assessed as parent compound remaining at 0.5 M measured after 10 mins | Rattus norvegicus | 15 | microsome format | Scientific Literature | ||
| 4. | ALA4835947 | A | Microsomal stability in monkey microsomes assessed as parent compound remaining at 0.5 M measured after 10 mins | Macaca mulatta | 15 | microsome format | Scientific Literature | ||
| 5. | ALA4835948 | A | Cmax in rat at 10 mg/kg, po | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
| 6. | ALA4835949 | F | Antagonist activity against human CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4835955 | F | Antimigraine activity in human CGRPalpha-induced migraine marmoset model assessed as reduction in facial blood flow at 7 mg/kg, sc administered 30 mins after CGRPalpha stimulation measured after 15 to 105 mins by laser doppler method relative to control | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4835960 | A | Cmax in Cynomolgus monkey at 10 mg/kg, po | Macaca fascicularis | 3 | organism-based format | Scientific Literature |
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