| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4839363 | B | Inhibition of DNA-PK (unknown origin) using biotin-PEG2-TWSLPLSQDSASE-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 2. | ALA4839364 | B | Displacement of 5-TAMRA-labelled Tracer A from human GST-fused/FLAG-tagged full length ATR/human N-terminal FLAG-tagged full length ATRIP expressed in HEK293-6E cells preincubated for 15 mins followed by tracer A addition and measured after 30 mins by TR-FRET based competition binding assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 3. | ALA4839365 | B | Inhibition of full-length N-terminal FLAG-tagged human ATM expressed in HEK293-6E cells using biotin-PEG2-SVEPPLSQETFSD as substrate preincubated for 15 mins followed by substrate addition and measured after 90 mins in presence of ATP by TR-FRET assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA4839366 | B | Inhibition of mTOR (unknown origin) using biotin-Ahx-PPGDYSTTPGGTLFSTTPGGTRI-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 5. | ALA4839367 | B | Inhibition of PI3Kbeta (unknown origin) using PI(4,5)P2 as substrate incubated for 60 mins in presence of ATP by ADP-Glo kinase assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 6. | ALA4839369 | B | Inhibition of DNA-PK in human HT-144 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA4839370 | B | Inhibition of PI3K in human MCF7 cells assessed as reduction in phosphorylation of AKT at Ser473 residue incubated for 30 mins by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA4839371 | B | Inhibition of ATR in human HT29 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature |
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