# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4837103 | B | Activation of full length PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 120 mins followed by addition of ADP-Glo max reagent incubated for 40 mins | Homo sapiens | 27 | single protein format | Scientific Literature | ||
2. | ALA4837104 | P | Solubility of compound by pH 7 measured for 24 hrs by UPLC analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA4837105 | A | Apparent permeability in dog MDCKII cells | Canis lupus familiaris | 7 | cell-based format | Scientific Literature | ||
4. | ALA4837106 | B | Activation of PKG1alpha (unknown origin) in human HEK293 cellls assessed as VSAP phosphorylation at Ser 239 incubated for 3 hrs by HTRF assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA5141582 | B | Activation of basal state recombinant PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 30 mins followed by ATP addition and measured after 2 hr by ADP-GLO Max Assay | Homo sapiens | 42 | single protein format | Scientific Literature | ||
6. | ALA5141583 | B | Activation of cGMP induced partially activated state recombinant PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 30 mins followed by ATP addition and measured after 2 hr in presence of cGMP by ADP-GLO Max Assay | Homo sapiens | 42 | single protein format | Scientific Literature | ||
7. | ALA5141584 | P | Solubility of compound at pH 7 | 5 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA5141585 | A | Apparent permeability in dog MDCK-II cells | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
9. | ALA5141586 | B | Activation of PKG1alpha in human HEK293 cells stably expressing VASP assessed as VSAP phosphorylation at Ser 239 incubated for 45 mins by HTRF assay | Homo sapiens | 5 | cell-based format | Scientific Literature |