# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831392 | Binding | Inhibition of CHK1 (unknown origin) incubated for 1 hr in presence of ATP by HTRF assay | Homo sapiens | 66 | ALA4828771 | single protein format | Scientific Literature | |
2. | ALA4831394 | Functional | Antiproliferation activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 64 | ALA4828771 | cell-based format | Scientific Literature | |
3. | ALA4831395 | Functional | Antiproliferation activity against human Z138 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 64 | ALA4828771 | cell-based format | Scientific Literature | |
4. | ALA4831396 | Binding | Inhibition of human ERG expressed in HEK293 cells at 10 uM by patch-clamp technique relative to control | Homo sapiens | 64 | ALA4828771 | cell-based format | Scientific Literature | |
5. | ALA4831397 | ADME | Half life in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature | |
6. | ALA4831398 | ADME | Tmax in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature | |
7. | ALA4831399 | ADME | Cmax in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature | |
8. | ALA4831400 | ADME | AUCt in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature | |
9. | ALA4831401 | ADME | AUC (0 to infinity) in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature | |
10. | ALA4831402 | ADME | MRT (0 to infinity) in ICR mouse at 20 mg/kg, po measured after 0.083 to 48 hrs by LC-MS/MS analysis | Mus musculus | 7 | ALA4828771 | organism-based format | Scientific Literature |