# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4824951 | B | Inhibition of Axl (unknown origin) by cell free assay | Homo sapiens | 32 | ALA4823291 | single protein format | Scientific Literature | |
2. | ALA4824952 | B | Inhibition of Mer (unknown origin) by cell free assay | Homo sapiens | 32 | ALA4823291 | single protein format | Scientific Literature | |
3. | ALA4824953 | B | Ratio of IC50 for Mer (unknown origin) to IC50 for Axl (unknown origin) | Homo sapiens | 31 | ALA4823291 | assay format | Scientific Literature | |
4. | ALA4824954 | B | Inhibition of Axl in mouse BaF3 cells | Mus musculus | 32 | ALA4823291 | cell-based format | Scientific Literature | |
5. | ALA4824955 | B | Inhibition of Mer in mouse BaF3 cells | Mus musculus | 32 | ALA4823291 | cell-based format | Scientific Literature | |
6. | ALA4824956 | B | Ratio of IC50 for Mer in mouse BaF3 cells to IC50 for Axl in mouse BaF3 cells | Mus musculus | 31 | ALA4823291 | cell-based format | Scientific Literature | |
7. | ALA4824957 | P | Solubility in PBS | 1 | ALA4823291 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4824958 | A | Permeability of compound by PAMPA assay | 1 | ALA4823291 | assay format | Scientific Literature | ||
9. | ALA4824959 | A | Metabolic stability in human liver microsomes assessed as residual ratio at 0.1 uM for 30 mins | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
10. | ALA4824960 | A | Metabolic stability in mouse liver microsomes assessed as residual ratio at 0.1 uM for 30 mins | Mus musculus | 1 | ALA4823291 | microsome format | Scientific Literature | |
11. | ALA4824961 | A | Time dependent inhibition of CYP1A2 in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
12. | ALA4824962 | A | Time dependent inhibition of CYP2C8 in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
13. | ALA4824963 | A | Time dependent inhibition of CYP2C9 in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
14. | ALA4824964 | A | Time dependent inhibition of CYP2C19 in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
15. | ALA4824965 | A | Time dependent inhibition of CYP2D6 in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
16. | ALA4824966 | A | Time dependent inhibition of CYP3A in human liver microsomes assessed as enzyme remaining activity using cocktail of probe CYP as substrate at 50 uM | Homo sapiens | 1 | ALA4823291 | microsome format | Scientific Literature | |
17. | ALA4824967 | A | Cmax in CAnN.Cg-Foxnlnu/CrlCrlj mouse plasma at 25 mg/kg, po single dose measured up to 24 hrs by liquid chromatography tandem mass spectrometry | Mus musculus | 1 | ALA4823291 | organism-based format | Scientific Literature | |
18. | ALA4824968 | A | Cmax in CAnN.Cg-Foxnlnu/CrlCrlj mouse plasma at 50 mg/kg, po single dose measured up to 24 hrs by liquid chromatography tandem mass spectrometry | Mus musculus | 1 | ALA4823291 | organism-based format | Scientific Literature | |
19. | ALA4824969 | A | Cmax in CAnN.Cg-Foxnlnu/CrlCrlj mouse plasma at 100 mg/kg, po single dose measured up to 24 hrs by liquid chromatography tandem mass spectrometry | Mus musculus | 1 | ALA4823291 | organism-based format | Scientific Literature | |
20. | ALA4824970 | A | AUC (0 to 24 hrs) in CAnN.Cg-Foxnlnu/CrlCrlj mouse plasma at 50 mg/kg, po single dose measured up to 24 hrs by liquid chromatography tandem mass spectrometry | Mus musculus | 1 | ALA4823291 | organism-based format | Scientific Literature |