# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4843199 | B | Agonist activity at human AMY3R (CT+RAMP3) expressed in Hollex1 cells incubated for 3 hrs by luminescence assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
2. | ALA4843200 | B | Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA4843201 | B | Ratio of EC50 for human calcitonin receptor expressed in BHK570 cells to EC50 for human AMY3R (CT+RAMP3) expressed in Hollex1 cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
4. | ALA4843202 | B | Agonist activity at rat AMY3R (CT+RAMP3) expressed in tk-ts13 cells assessed as increase in intracellular cAMP level incuabted for 25 mins by CRE luciferase reporter gene assay | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
5. | ALA4843203 | B | Agonist activity at rat calcitonin receptor expressed in BHK-13 cells assessed as increase in intracellular cAMP concentration incubated for 25 mins by CRE luciferase reporter gene assay | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
6. | ALA4843204 | B | Ratio of EC50 for rat calcitonin receptor expressed in BHK-13 cells to EC50 for rat AMY3R (CT+RAMP3) expressed in tk-ts13 cells | Rattus norvegicus | 23 | cell-based format | Scientific Literature | ||
7. | ALA4843205 | B | Displacement of [125I]-amylin from human AMY3R (CTR+RAMP3) expressed in BHK-13 cells measured after 120 mins by scintillation proximity assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
8. | ALA4843206 | B | Displacement of [125I]-calcitonin from human calcitonin receptor expressed in tk-ts 13 cells measured after 120 mins by scintillation proximity assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
9. | ALA4843207 | B | Ratio of IC50 for displacement of [125I]-calcitonin from human calcitonin receptor expressed in tk-ts 13 cells to IC50 for displacement of [125I]-amylin from human AMY3R (CTR+RAMP3) expressed in BHK-13 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
10. | ALA4843208 | B | Displacement of [125I]-amylin from rat AMY3R (CTR+RAMP3) expressed in BHK-13 cells measured after 120 mins by scintillation proximity assay | Rattus norvegicus | 19 | cell-based format | Scientific Literature | ||
11. | ALA4843209 | B | Displacement of [125I]-calcitonin from rat calcitonin receptor expressed in tk-ts 13 cells measured after 120 mins by scintillation proximity assay | Rattus norvegicus | 19 | cell-based format | Scientific Literature | ||
12. | ALA4843210 | B | Ratio of IC50 for displacement of [125I]-calcitonin from rat calcitonin receptor expressed in tk-ts 13 cells to IC50 for displacement of [125I]-amylin from rat AMY3R (CTR+RAMP3) expressed in BHK-13 cells | Rattus norvegicus | 16 | cell-based format | Scientific Literature | ||
13. | ALA4843211 | P | Solubility of the compound in lactate at pH 3 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA4843212 | P | Solubility of the compound in lactate at pH 4 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA4843213 | P | Solubility of the compound in lactate at pH 5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA4843214 | P | Solubility of the compound in bis-tris propane at pH 6 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA4843215 | P | Solubility of the compound in bis-tris propane at pH 6.5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
18. | ALA4843216 | P | Solubility of the compound in bis-tris propane at pH 7 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
19. | ALA4843217 | P | Solubility of the compound in bis-tris propane at pH 7.5 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
20. | ALA4843218 | P | Solubility of the compound in bis-tris propane at pH 8 by UPLC analysis | 27 | small-molecule physicochemical format | Scientific Literature |