# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831196 | ADME | Cytotoxicity against HDF assessed as cell viability at 10 uM incubated for 72 hrs by MTS assay | Homo sapiens | 12 | ALA4828764 | cell-based format | Scientific Literature | |
2. | ALA4831197 | Binding | Inhibition of MEIS1 (unknown origin) expressed in HEK293T cells co-expressing MEIS-Luc-pGL2 assessed as luciferase activity at 10 uM incubated for 48 hrs by luciferase reporter assay related to protein content | Homo sapiens | 46 | ALA4828764 | cell-based format | Scientific Literature | |
3. | ALA4831198 | Binding | Inhibition of MEIS1 (unknown origin) expressed in HEK293T cells co-expressing MEIS-Luc-pGL2 assessed as luciferase activity at 10 uM incubated for 48 hrs by luciferase reporter assay related to beta-galactose control | Homo sapiens | 46 | ALA4828764 | cell-based format | Scientific Literature | |
4. | ALA4831199 | Binding | Inhibition of MEIS1 (unknown origin) expressed in HEK293T cells co-expressing MEIS-Luc-pGL2 assessed as downregulation of Meis1 gene expression measuring mRNA level at 10 uM incubated for 2 days by RT-qPCR analysis | Homo sapiens | 13 | ALA4828764 | cell-based format | Scientific Literature | |
5. | ALA4831200 | Binding | Inhibition of MEIS1 (unknown origin) expressed in HEK293T cells co-expressing MEIS-Luc-pGL2 assessed as downregulation of Hif-Ialpha gene expression measuring mRNA level at 10 uM incubated for 2 days by RT-qPCR analysis | Homo sapiens | 12 | ALA4828764 | cell-based format | Scientific Literature | |
6. | ALA4831201 | Binding | Inhibition of MEIS1 (unknown origin) expressed in HEK293T cells co-expressing MEIS-Luc-pGL2 assessed as downregulation of p21 gene expression by measuring mRNA level at 10 uM incubated for 2 days by RT-qPCR analysis | Homo sapiens | 13 | ALA4828764 | cell-based format | Scientific Literature |