# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4808312 | B | Binding affinity to Zn(II)+ incubated for 60 mins using RhodZin-3 by fuorescence assay | 30 | assay format | Scientific Literature | |||
2. | ALA4808313 | B | Binding affinity to Zn(II)+ incubated for 60 mins using FluoZin-3 by fuorescence assay | 29 | assay format | Scientific Literature | |||
3. | ALA4808314 | F | Growth inhibition of human TOV112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
4. | ALA4808315 | F | Ratio of EC50 for test compound to EC50 for ZMC1 for growth inhibition of human TOV-112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay | Homo sapiens | 29 | tissue-based format | Scientific Literature | ||
5. | ALA4808316 | F | Induction of ROS production in human H1299 cells at 0.75 uM incubated for 24 hrs by CellRox green based fluorescence flow cytometry relative to ZMC1 | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
6. | ALA4808317 | A | Apparent permeability in human Caco-2 cells at 5 uM measured up to 90 mins by LC-MS/MS analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
7. | ALA4808318 | B | Induction of Zinc-dependent p53 R175H mutant refolding by assessing wild type conformation | 29 | assay format | Scientific Literature | |||
8. | ALA4808321 | A | Displacement of [3H]DAMGO from human recombinant mu receptor at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 11 | single protein format | Scientific Literature | ||
9. | ALA4808322 | B | Displacement of [3H]-dofetilide from human recombinant ERG at 10 uM relative to control | Homo sapiens | 11 | single protein format | Scientific Literature | ||
10. | ALA4808323 | A | Displacement of [125I]+/-DOI from human recombinant 5-HT2A receptor at 10 uM after 60 mins by scintillation counting analysis relative to control | Homo sapiens | 11 | single protein format | Scientific Literature | ||
11. | ALA4808324 | A | Displacement of [3H]batrachotoxinin from rat Sodium channel site 2 at 10 uM incubated for 60 mins by radiometric scintillation analysis relative to control | Rattus norvegicus | 11 | assay format | Scientific Literature | ||
12. | ALA4808325 | A | Displacement of [3H]nisoxetine from recombinant human norepinephrine transporter at 10 uM incubated for 120 mins by radiometric scintillation analysis relative to control | Homo sapiens | 11 | single protein format | Scientific Literature | ||
13. | ALA4808329 | F | Anticancer activity against human TOV112D cells harbouring p53 R175H mutant xenografted NCr nu/nu mouse assessed as tumor growth inhibition at 5.73 mg/kg, ip relative to control | Homo sapiens | 5 | organism-based format | Scientific Literature |