| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4843234 | B | Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA4843237 | B | Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assay | Homo sapiens | 62 | cell-based format | Scientific Literature | ||
| 3. | ALA4843244 | A | Clearance in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 4. | ALA4843245 | A | Volume of distribution at steady state in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA4843246 | A | Terminal half life in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA4843247 | A | AUC (0 to infinity) in CD-1 mouse at 0.3 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA4843248 | A | Cmax in CD-1 mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA4843249 | A | Oral bioavailability in CD-1 mouse at 10 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 9. | ALA4843250 | B | Inhibition of human ERG by fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 10. | ALA4843252 | B | Inhibition of human ERG by Qpatch method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA4843253 | B | Inhibition of human ERG by manual patch clamp method | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 12. | ALA4843254 | B | Selectivity ratio of IC50 for inhibition of human ERG by manual patch clamp method to IC50 for inhibition of IDO1 in human HeLa cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA4843260 | A | Intrinsic clearance in rat hepatocytes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4843261 | A | Half life in rat hepatocytes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4843262 | A | Drug concentration in tumor of NSG mouse xenografted with human SKOV3 cells at 125 mg/kg, po QD administered for 5 days and measured 24 hrs post dose | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 16. | ALA4843276 | A | Protein binding in human plasma at 5 uM incubated for 5 hrs by rapid equilibrium dialysis | Homo sapiens | 45 | cell-free format | Scientific Literature | ||
| 17. | ALA4843280 | A | Inhibition of CYP2C9 in human liver microsomes using sulfaphenazole as substrate incubated for 10 mins in presence of NADPH by LCMS/MS analysis | Homo sapiens | 27 | microsome format | Scientific Literature | ||
| 18. | ALA4843281 | B | Displacement of Tracer Red from human ERG measured after 4 hrs by fluorescence polarization assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 19. | ALA4843283 | A | Intrinsic clearance in Beagle dog liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis | Canis lupus familiaris | 1 | microsome format | Scientific Literature | ||
| 20. | ALA4843284 | A | Bioavailability in Beagle dog measured at 0.083 to 24 hrs by LC-MS/MS method | Canis lupus familiaris | 1 | organism-based format | Scientific Literature |
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