# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4826390 | F | Antiproliferative activity against human MDA-MB-231 cells | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
2. | ALA4826391 | F | Antiproliferative activity against human MGC-803 cells | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
3. | ALA4826392 | F | Antiproliferative activity against human A549 cells | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
4. | ALA4826393 | A | Metabolic stability in human liver microsomes assessed as clearance at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
5. | ALA4826394 | A | Metabolic stability in human liver microsomes assessed as half life at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured upto 60 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
6. | ALA4826395 | F | Antitumor activity against human MDA231-LM2-4175 cells xenografted in mouse assessed as reduction in pY705-STAT3 expression at 5 to 15 mg/kg, iv administered once daily for 20 days by Western blotting analysis | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
7. | ALA4826396 | B | Binding affinity to STAT3 (unknown origin) by SRB assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA4826397 | B | Inhibition of STAT3 phosphorylation at Tyr705 residue in human MDA-MB-231 cells after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4826398 | B | Inhibition of STAT3 phosphorylation at Tyr705 residue in human MDA-MB-469 cells after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4826399 | B | Inhibition of STAT3 phosphorylation at Tyr705 residue in human HCC70 cells after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4826400 | B | Inhibition of STAT3 phosphorylation at Tyr705 residue in human MDA231-LM2-4175 cells after 3 hrs by Western blotting analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
12. | ALA4826401 | F | Effect on total STAT3 level in human MDA-MB-231 cells at 0.3 to 3 uM measured after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4826402 | F | Effect on total STAT3 level in human MDA-MB-468 cells at 0.3 to 3 uM measured after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4826403 | F | Effect on total STAT3 level in human HCC70 cells at 0.3 to 3 uM measured after 3 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4826404 | F | Effect on total STAT3 level in human MDA231-LM2-4175 cells at 0.3 to 3 uM measured after 3 hrs by Western blot analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
16. | ALA4826405 | B | Inhibition of STAT3 phosphorylation at Ser727 residue in human MDA-MB-231 cells at 3 uM after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4826406 | B | Inhibition of STAT3 phosphorylation at Ser727 residue in human MDA-MB-231-4175 cells at 3 uM after 3 hrs by Western blotting analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
18. | ALA4826407 | B | Inhibition of STAT3 phosphorylation at Ser727 residue in human MDA-MB-468 cells at 3 uM after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4826408 | B | Inhibition of STAT3 phosphorylation at Ser727 residue in human HCC70 cells at 3 uM after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4826409 | B | Inhibition of STAT1 phosphorylation at Y701 residue in human MDA-MB-231 cells at 0.3 to 3 uM after 3 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |