# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821189 | Binding | Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 30 uM incubated for 5 mins by two electrode voltage-clamp assay relative to control | Homo sapiens | 2 | ALA4819053 | cell-based format | Scientific Literature | |
2. | ALA4821190 | Binding | Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2-alpha1B channel assessed as inhibition of CaV2.2-mediated Ba2+ peak-current amplitude at 100 nM at -80 to 10 mV holding potential after 72 hrs by whole cell patch clamp assay relative to control | Homo sapiens | 3 | ALA4819053 | cell-based format | Scientific Literature | |
3. | ALA4821191 | Binding | Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2-alpha2delta1 channel assessed as inhibition of CaV2.2-mediated Ba2+ peak-current amplitude at 100 nM at -80 to 10 mV holding potential after 72 hrs by whole cell patch clamp assay relative to control | Homo sapiens | 3 | ALA4819053 | cell-based format | Scientific Literature | |
4. | ALA4821192 | Binding | Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2-beta3 channel assessed as inhibition of CaV2.2-mediated Ba2+ peak-current amplitude at 100 nM at -80 to 10 mV holding potential after 72 hrs by whole cell patch clamp assay relative to control | Homo sapiens | 3 | ALA4819053 | cell-based format | Scientific Literature |