# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4833229 | Binding | Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse J774A.1 cells assessed as inhibition of cell pyrolysis at 20 uM incubated for 1 hr followed by ATP addition and measured after 30 mins by Hoechst 33342/propidium iodide staining based high content screening method relative to control | Mus musculus | 34 | ALA4831528 | tissue-based format | Scientific Literature | |
2. | ALA4833230 | ADME | Cytotoxicity against human L-02 cells incubated for 24 hrs by MTT assay | Homo sapiens | 53 | ALA4831528 | cell-based format | Scientific Literature | |
3. | ALA4833231 | Binding | Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse J774A.1 cells assessed as inhibition of cell pyrolysis at 10 uM incubated for 1 hr followed by ATP addition and measured after 30 mins by Hoechst 33342/propidium iodide staining based high content screening method relative to control | Mus musculus | 50 | ALA4831528 | tissue-based format | Scientific Literature |