# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4832570 | B | Displacement of 1,8-ANS from FABP4 (unknown origin) at 25 uM incubated for 3 mins by fluorescence based analysis relative to control | Homo sapiens | 30 | single protein format | Scientific Literature | ||
2. | ALA4832571 | B | Displacement of 1,8-ANS from FABP5 (unknown origin) at 25 uM incubated for 3 mins by fluorescence based analysis relative to control | Homo sapiens | 30 | single protein format | Scientific Literature | ||
3. | ALA4832572 | B | Displacement of 1,8-ANS from FABP4 (unknown origin) incubated for 3 mins by fluorescence based analysis | Homo sapiens | 30 | single protein format | Scientific Literature | ||
4. | ALA4832573 | B | Displacement of 1,8-ANS from FABP5 (unknown origin) incubated for 3 mins by fluorescence based analysis | Homo sapiens | 30 | single protein format | Scientific Literature | ||
5. | ALA4832577 | A | Metabolic stability in mouse liver microsomes assessed as half life at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured for 60 mins by LC-MS/MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
6. | ALA4832578 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured for 60 mins per gm protein by LC-MS/MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
7. | ALA4832597 | F | Anti-lipolytic activity in mouse 3T3-L1 cells assessed as inhibition of forskolin-stimulated glycerol release at 80 uM preincubated for 24 hrs followed by forskolin stimulation for 1 hr | Mus musculus | 7 | cell-based format | Scientific Literature | ||
8. | ALA4832600 | A | Cytotoxicity against mouse 3T3-L1 cells assessed as reduction in cell viability at 100 uM incubated for 24 hrs by CCK8 assay | Mus musculus | 9 | cell-based format | Scientific Literature |