| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835865 | F | Antiviral activity against HBV infected in human HepG2-NTCP cells assessed as reduction in HBeAg secretion incubated for 24 hrs followed replacement with fresh medium and measured at day 5 post infection by ELISA | Hepatitis B virus | 41 | organism-based format | Scientific Literature | ||
| 2. | ALA4835901 | A | Stability in mouse liver microsomes assessed as half life at 1 uM preincubated for 5 mins followed by NADPH addition and measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 3. | ALA4835902 | A | Stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 5 mins followed by NADPH addition and measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 4. | ALA4835903 | B | Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells in presence of 20 % FBS | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4835904 | B | Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells in presence of 50 % FBS | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4835905 | B | Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells pretreated for 2 hrs followed by [3H]-TCA addition in absence of FBS | Homo sapiens | 6 | cell-based format | Scientific Literature |
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