# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831906 | B | Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +60 mV in presence of CBX at 50 uM measured by Whole cell voltage clamp assay relative to control | Mus musculus | 27 | cell-based format | Scientific Literature | ||
2. | ALA4831907 | B | Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +60 mV in presence of CBX measured by Whole cell voltage clamp assay relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
3. | ALA4831909 | B | Inhibition of human P2X7R expressed in Xenopus laevis oocytes assessed as inhibition of BzATP-induced cell membrane current at 10 uM measured by Whole cell voltage clamp assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4831910 | B | Inhibition of wild type Cx32(E143) (unknown origin) expressed in Xenopus laevis oocytes assessed as at holding potential of -10 mV and stepped in 5 mV test pulses of 5 sec duration at 10 uM measured by Voltage clamp assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4831912 | F | Antiallodynic activity in oxaliplatin-induced neuropathy pain IT dosed CD-1 mouse model assessed as reversal of enhancement of pain threshold by measuring minimum effective dose measured 60 to 75 mins by cold plate assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4831913 | F | Antiallodynic activity in oxaliplatin-induced neuropathy pain CD-1 mouse model assessed as reversal of enhancement of pain threshold at 1 nmol, IT measured after 45 to 90 mins by cold plate assay | Mus musculus | 1 | organism-based format | Scientific Literature |