| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4829821 | F | Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA4829822 | F | Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 3. | ALA4829823 | F | Antiproliferative activity against human RPMI-7951 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 4. | ALA4829824 | F | Antiproliferative activity against human MDA-MB-453 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 5. | ALA4829825 | F | Antiproliferative activity against human SK-BR-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 6. | ALA4829826 | F | Antiproliferative activity against human MDA-MB-435/LCC6MDR cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 7. | ALA4829827 | F | Resistance index, ratio of IC50 for antiproliferation activity against human MDA-MB-435/LCC6MDR cells to IC50 for antiproliferation activity against human MDA-MB-435 cells assessed as cell growth inhibition measured after 72 hrs by MTS assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 8. | ALA4829828 | F | Antiproliferative activity against human OVCAR-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4829829 | F | Antiproliferative activity against human OVCAR-8 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4829830 | F | Downregulation of survivin protein expression in human A-375 cells measured after 24 hrs by Westernblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4829832 | F | Induction of apoptosis in human A-375 cells assessed as increase in cleaved PARP level after 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4829833 | F | Induction of apoptosis in human A-375 cells assessed as increase in cleaved ADP-ribose level after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4829834 | F | Downregulation of survivin protein expression in human OVCAR-8 cells measured after 24 hrs by Westernblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4829835 | F | Downregulation of survivin protein expression in human OVCAR-3 cells measured after 24 hrs by Westernblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4829836 | F | Downregulation of survivin protein expression in human SK-OV-3 cells measured after 24 hrs by Westernblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4829837 | A | Metabolic stability of the compound in mouse liver microsomes assessed as half life at 10 uM incubated for 10 mins in presence of NADPH by UPLC-MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
| 17. | ALA4829838 | A | Metabolic stability of the compound in rat liver microsomes assessed as half life at 10 uM incubated for 10 mins in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 7 | microsome format | Scientific Literature | ||
| 18. | ALA4829839 | A | Metabolic stability of the compound in human liver microsomes assessed as half life at 10 uM incubated for 10 mins in presence of NADPH by UPLC-MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 19. | ALA4829840 | A | Metabolic stability of the compound in mouse liver microsomes assessed as clearance at 10 uM incubated for 10 mins in presence of NADPH by UPLC-MS analysis | Mus musculus | 7 | microsome format | Scientific Literature | ||
| 20. | ALA4829841 | A | Metabolic stability of the compound in rat liver microsomes assessed as clearance at 10 uM incubated for 10 mins in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 7 | microsome format | Scientific Literature |
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