# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4825557 | B | Inhibition of recombinant porcine PREP expressed in Escherichia coli using Suc-Gly-Pro-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by multilabel counter analysis | Sus scrofa | 20 | assay format | Scientific Literature | ||
2. | ALA4825558 | B | Inhibition of porcine PREP expressed in Escherichia coli at 1 nM using Suc-Gly-Pro-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by multilabel counter analysis relative to control | Sus scrofa | 4 | assay format | Scientific Literature | ||
3. | ALA4825559 | B | Inhibition of human PREP expressed in N2A cells assessed as decrease in alpha-synuclein dimerization by measuring decrease in luminescence at 10 uM measured after 4 hrs by protein fragment complementation assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
4. | ALA4825560 | F | Induction of autophagy in human HEK293 cells expressing GFP-LC3B-RFP assessed as decrease in fluorescence at 10 uM after 24 hrs by multilabel counter method | Homo sapiens | 25 | cell-based format | Scientific Literature |