| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4843875 | B | Inhibition of full-length N-terminal GST tagged BTK (1 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA | Homo sapiens | 69 | cell-based format | Scientific Literature | ||
| 2. | ALA4843876 | B | Inhibition of N-terminal DYKDDDD-tagged EGFR (669 to 1210 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4843877 | B | Inhibition of N-terminal GST-tagged BMX (1 to 675 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA4843878 | B | Inhibition of N-terminal GST-tagged ITK (2 to 620 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4843879 | B | Selectivity index, ratio of IC50 for inhibition of EGFR (unknown origin) to IC50 for inhibition of BTK (unknown origin) | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 6. | ALA4843880 | B | Selectivity index, ratio of IC50 for inhibition of BMX (unknown origin) to IC50 for inhibition of BTK (unknown origin) | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 7. | ALA4843881 | B | Selectivity index, ratio of IC50 for inhibition of ITK (unknown origin) to IC50 for inhibition of BTK (unknown origin) | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 8. | ALA4843882 | F | Antiproliferative activity against human TMD8 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4843883 | F | Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA4843884 | F | Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4843885 | A | Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4843886 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at 30 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 100 %) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4843887 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at G1 phase at 30 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 54.27 %) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA4843888 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at G2 phase at 30 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 4.99 %) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4843889 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at S phase at 30 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 40.74 %) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4843890 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at 300 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 100 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4843891 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at G1 phase at 300 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 54.27 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4843892 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at G2 phase at 300 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 4.99 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4843893 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at S phase at 300 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 40.74 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4843894 | F | Induction of cell cycle arrest in human TMD8 cells assessed as accumulation of diploid cells at 3 nM incubated for 48 hrs by PI staining based flow cytometric analysis (Rvb = 100 %) | Homo sapiens | 2 | cell-based format | Scientific Literature |
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