| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4835353 | B | Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiology | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA4835354 | B | Inhibition of human TRPM2 expressed in HEK293T cells assessed as suppression of H2O2-induced calcium flux at 30 uM measured after 30 mins by Fluo-3/AM assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4835355 | A | Cytotoxicity against human SH-SY5Y cells assessed as toxicity at 30 uM incubated for 24 hrs by CCK-8 assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA4835356 | B | Inhibition of human TRPM8 expressed in HEK293T cells assessed as blocked of menthol-activated current at 10 uM by whole cell patch clamp electrophysiology relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA4835359 | B | Inhibition of mouse TRPM1 expressed in HEK293T cells assessed as blocked of capsaicin-activated current at 10 uM by whole cell patch clamp electrophysiology relative to control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4835360 | B | Inhibition of PLA2 (unknown origin) using soybean phosphatidylcholine as substrate at 10 uM preincubated for 30 mins followed incubated for 60 mins after substrate addition by microplate reader relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 7. | ALA4835363 | F | Neuroprotective activity against oxygen glucose deprivation/reperfusion-induced cell death in human SH-SY5Y cells assessed as cell viability at 3 uM preincubated for 8 hrs followed by OGD and reperfusion for 12 hrs by CCK8 assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA4835366 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability under normoxic/normal sugar condition at 10 to 30 uM by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4835403 | B | Inhibition of human TRPM2 expressed in HEK293T cells assessed as suppression of H2O2-induced calcium flux at 1 uM measured after 30 mins by Fluo-3/AM assay | Homo sapiens | 60 | cell-based format | Scientific Literature |
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