# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4826336 | B | Inhibition of human recombinant LSD1 by horseradish peroxidase-coupled fluorometric assay | Homo sapiens | 40 | ALA4825677 | single protein format | Scientific Literature | |
2. | ALA4826337 | B | Inhibition of N-terminal FLAG-tagged human recombinant MAO-A expressed in baculovirus-infected Sf9 cells by flow cytometry | Homo sapiens | 3 | ALA4825677 | cell-based format | Scientific Literature | |
3. | ALA4826338 | B | Inhibition of N-terminal FLAG-tagged human recombinant MAO-B expressed in baculovirus-infected Sf9 cells by flow cytometry | Homo sapiens | 3 | ALA4825677 | cell-based format | Scientific Literature | |
4. | ALA4826339 | B | Selectivity index, ratio of IC50 for N-terminal FLAG-tagged human recombinant MAO-A expressed in baculovirus-infected Sf9 cells to IC50 for human recombinant LSD1 | Homo sapiens | 3 | ALA4825677 | cell-based format | Scientific Literature | |
5. | ALA4826340 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
6. | ALA4826341 | F | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
7. | ALA4826342 | F | Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
8. | ALA4826343 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
9. | ALA4826344 | F | Antiproliferative activity against human THP-1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
10. | ALA4826345 | A | Cytotoxicity against human THLE-2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 6 | ALA4825677 | cell-based format | Scientific Literature | |
11. | ALA4826346 | A | Metabolic stability in human liver microsomes assessed as half-life by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
12. | ALA4826347 | A | Metabolic stability in human liver microsome assessed as intrinsic clearance by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
13. | ALA4826348 | A | Metabolic stability in human liver assessed as intrinsic clearance by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | tissue-based format | Scientific Literature | |
14. | ALA4826349 | A | Microsomal stability in human liver microsomes assessed as parent compound remaining after 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
15. | ALA4826350 | A | Microsomal stability in human liver microsomes assessed as parent compound remaining after 60 mins in absence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
16. | ALA4826351 | A | Inhibition of CYP2C9 in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
17. | ALA4826352 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
18. | ALA4826353 | A | Inhibition of CYP2D6 in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
19. | ALA4826354 | A | Inhibition of CYP3A4 in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature | |
20. | ALA4826355 | A | Inhibition of CYP1A2 in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 4 | ALA4825677 | microsome format | Scientific Literature |