# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4822225 | Binding | Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assay | Homo sapiens | 32 | ALA4819104 | assay format | Scientific Literature | |
2. | ALA4822226 | Binding | Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assay | Homo sapiens | 30 | ALA4819104 | single protein format | Scientific Literature | |
3. | ALA4822227 | Physicochemical | Aqueous solubility of the compound | 6 | ALA4819104 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4822228 | ADME | Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells | Homo sapiens | 6 | ALA4819104 | cell-based format | Scientific Literature | |
5. | ALA4822229 | ADME | Efflux ratio of apparent permeability in human Caco-2 cells | Homo sapiens | 6 | ALA4819104 | cell-based format | Scientific Literature | |
6. | ALA4822230 | ADME | Plasma protein binding in human | Homo sapiens | 6 | ALA4819104 | cell-free format | Scientific Literature | |
7. | ALA4822231 | ADME | Plasma protein binding in rat | Rattus norvegicus | 6 | ALA4819104 | cell-free format | Scientific Literature | |
8. | ALA4822232 | ADME | Plasma protein binding in mouse | Mus musculus | 6 | ALA4819104 | cell-free format | Scientific Literature | |
9. | ALA4822233 | ADME | Plasma protein binding in dog | Canis lupus familiaris | 6 | ALA4819104 | cell-free format | Scientific Literature | |
10. | ALA4822234 | ADME | Half life in human hepatocytes | Homo sapiens | 6 | ALA4819104 | cell-based format | Scientific Literature | |
11. | ALA4822235 | ADME | Half life in rat hepatocytes | Rattus norvegicus | 6 | ALA4819104 | cell-based format | Scientific Literature | |
12. | ALA4822236 | ADME | Half life in mouse hepatocytes | Mus musculus | 6 | ALA4819104 | cell-based format | Scientific Literature | |
13. | ALA4822237 | ADME | Half life in dog hepatocytes | Canis lupus familiaris | 6 | ALA4819104 | cell-based format | Scientific Literature |