| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4815065 | B | Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assay | Human immunodeficiency virus 1 | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA4815066 | B | Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assay | Human immunodeficiency virus 1 | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4815067 | A | Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by Cell Titer-Glo assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 4. | ALA4815099 | F | Potentiation of KD-247-induced viral neutralizing activity against SHIV KS2661 infected in human TZM-bl cells assessed as KD-247 IC50 for viral neutralization at 5 uM measured after 48 hrs by luciferase assay (Rvb = 2.422 ug/ml) | Simian immunodeficiency virus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA4815100 | F | Potentiation of KD-247-induced viral neutralizing activity against SHIV KS2661 infected in human TZM-bl cells assessed as KD-247 IC50 for viral neutralization at 10 uM measured after 48 hrs by luciferase assay (Rvb = 2.422 ug/ml) | Simian immunodeficiency virus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA4815101 | F | Potentiation of KD-247-induced viral neutralizing activity against SHIV KS2661 infected in human TZM-bl cells assessed as KD-247 IC50 for viral neutralization at 20 uM measured after 48 hrs by luciferase assay (Rvb = 2.422 ug/ml) | Simian immunodeficiency virus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA5133924 | B | CD4 mimetic activity at gp120 in HIV-1 KP-5mvcR infected in human TZM-bl cells assessed as inhibition of viral entry by measuring reduction in RLU by single round assay | Human immunodeficiency virus 1 | 11 | cell-based format | Scientific Literature | ||
| 8. | ALA5133925 | T | Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTiter-Glo 2.0 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA5133926 | P | Aqueous solubility of the compound in PBS at pH 7.4 at 25 degC | 9 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA5133927 | T | Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability at <100 uM by CellTiter-Glo 2.0 assay | Homo sapiens | 9 | cell-based format | Scientific Literature |
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