# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4814428 | B | Inhibition of human LSD1 (172 to 833 residues) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
2. | ALA4814429 | B | Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA4814430 | B | Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by peroxidase-coupled assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA4814431 | B | Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate incubated for 30 mins by fluorescence method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA5053594 | A | Antiproliferative activity against human WI-38 cells after 72 hrs by alamarBlue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA5135944 | B | Inhibition of human LSD1 assessed as demethylase activity of LSD1 using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate addition by peroxidase-coupled reaction assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
7. | ALA5135945 | B | Inhibition of human LSD1 assessed Kinact using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate addition by peroxidase-coupled reaction assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
8. | ALA5135946 | B | Inhibition of human LSD1 assessed as inhibitory constant using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate addition by peroxidase-coupled reaction assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
9. | ALA5135947 | B | Inhibition of human LSD1 assessed as ratio of Kinact/Ki using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate addition by peroxidase-coupled reaction assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
10. | ALA5135948 | T | Inhibition of human ERG expressed in human HEK293 cells at 10 uM for 2 mins by whole-cell patch-clamp system | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
11. | ALA5135954 | A | AUC (0-infinity) in ICR mouse at 10 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA5135955 | A | Cmax in ICR mouse serum at 10 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
13. | ALA5135956 | A | Tmax in ICR mouse serum at 10 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA5135957 | A | Half life in ICR mouse serum at 10 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA5135958 | B | Inhibition of human LSD1 in human Jurkat cells assessed as downregulation of NOTCH3 expression at 10 uM for 12 hrs by Real-Time PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |