| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4808684 | A | Bioavailability in Wistar rat at 0.5 mg/kg, iv measured upto 24 hrs by HPLC-MS/MS method | Rattus norvegicus | 1 | ALA4808172 | organism-based format | Scientific Literature | |
| 2. | ALA4808685 | F | Reversal of CCI-induced mechano-allodynia in mouse model of neuropathic pain at 10 umol/kg, ip after 1 hr | Mus musculus | 1 | ALA4808172 | organism-based format | Scientific Literature | |
| 3. | ALA4808686 | B | Inhibition of fluorescent antagonist binding to human P2Y14 receptor expressed in CHO cells preincubated with compound for 30 mins followed by fluorescent antagonist addition and measured after 30 mins by flow cytometry analysis | Homo sapiens | 33 | ALA4808172 | cell-based format | Scientific Literature | |
| 4. | ALA4808687 | B | Inhibition of fluorescent antagonist binding to mouse P2Y14 receptor expressed in HEK293 cells preincubated with compound for 30 mins followed by fluorescent antagonist addition and measured after 30 mins by flow cytometry analysis | Mus musculus | 4 | ALA4808172 | cell-based format | Scientific Literature | |
| 5. | ALA4808688 | P | Aqueous solubility of compound at pH 7.4 | 2 | ALA4808172 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4808689 | P | Aqueous solubility of compound at pH 4.0 | 2 | ALA4808172 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4808690 | B | Binding affinity to sigma 1 receptor (unknown origin) | Homo sapiens | 3 | ALA4808172 | single protein format | Scientific Literature | |
| 8. | ALA4808691 | B | Binding affinity to sigma 2 receptor (unknown origin) | Homo sapiens | 4 | ALA4808172 | single protein format | Scientific Literature | |
| 9. | ALA4808693 | B | Binding affinity to TSPO (unknown origin) | Homo sapiens | 4 | ALA4808172 | single protein format | Scientific Literature | |
| 10. | ALA4808709 | A | Stability of compound in stimulated intestinal fluid assessed as half life | 1 | ALA4808172 | assay format | Scientific Literature | ||
| 11. | ALA4808710 | A | Stability of compound in stimulated gastric fluid assessed as half life | 1 | ALA4808172 | assay format | Scientific Literature | ||
| 12. | ALA4808711 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA4808172 | single protein format | Scientific Literature | |
| 13. | ALA4808712 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4808172 | single protein format | Scientific Literature | |
| 14. | ALA4808713 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA4808172 | single protein format | Scientific Literature | |
| 15. | ALA4808714 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA4808172 | single protein format | Scientific Literature | |
| 16. | ALA4808715 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA4808172 | single protein format | Scientific Literature | |
| 17. | ALA4808716 | A | Stability in rat plasma assessed as half life | Rattus norvegicus | 1 | ALA4808172 | cell-free format | Scientific Literature | |
| 18. | ALA4808717 | A | Stability in mouse plasma assessed as half life | Mus musculus | 1 | ALA4808172 | cell-free format | Scientific Literature | |
| 19. | ALA4808718 | A | Microsomal stability in human liver microsomes assessed as half life | Homo sapiens | 1 | ALA4808172 | microsome format | Scientific Literature | |
| 20. | ALA4808719 | A | Microsomal stability in rat liver microsomes assessed as half life | Rattus norvegicus | 1 | ALA4808172 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!