# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4824266 | Functional | Leishmanicidal activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells assessed as reduction in intracellular amastigotes incubated for 24 hrs by propidium iodide staining based flow cytometry | Leishmania infantum | 13 | ALA4823264 | organism-based format | Scientific Literature | |
2. | ALA4824267 | ADME | Cytotoxicity against human THP-1 cells by LDH assay | Homo sapiens | 13 | ALA4823264 | cell-based format | Scientific Literature | |
3. | ALA4824269 | Toxicity | Selectivity index, ratio of EC50 for human THP-1 macrophage cells to EC50 for Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells | 2 | ALA4823264 | assay format | Scientific Literature |