| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4838784 | B | Inhibition of [3H]Colchicine binding to tubulin (unknown origin) at 5 uM measured after 10 mins by DEAE-Cellulose filter method relative to control | Homo sapiens | 26 | ALA4837226 | protein complex format | Scientific Literature | |
| 2. | ALA4838785 | B | Inhibition of tubulin polymerization (unknown origin) assessed as reduction in tubulin assembly preincubated for 15 mins followed by GTP addition by spectrophotometric method | Homo sapiens | 26 | ALA4837226 | protein complex format | Scientific Literature | |
| 3. | ALA4838786 | B | Inhibition of [3H]Colchicine binding to tubulin (unknown origin) at 1 uM measured after 10 mins by DEAE-Cellulose filter method relative to control | Homo sapiens | 10 | ALA4837226 | protein complex format | Scientific Literature | |
| 4. | ALA4838787 | F | Cytotoxicity against human MCF7 cells assessed as cell growth inhibition measured after 96 hrs | Homo sapiens | 25 | ALA4837226 | cell-based format | Scientific Literature | |
| 5. | ALA4838788 | F | Cytotoxicity against human U-343MG cells assessed as cell growth inhibition measured after 72 hrs by MTS colorimetric assay | Homo sapiens | 2 | ALA4837226 | cell-based format | Scientific Literature | |
| 6. | ALA4838789 | F | Cytotoxicity against human U343MG cells assessed as cell growth inhibition by measuring maximum efficacy measured after 72 hrs by MTS colorimetric assay relative to control | Homo sapiens | 2 | ALA4837226 | cell-based format | Scientific Literature | |
| 7. | ALA4838790 | F | Cytotoxicity against human U-87MG cells assessed as cell growth inhibition measured after 48 hrs by MTS colorimetric assay | Homo sapiens | 2 | ALA4837226 | cell-based format | Scientific Literature | |
| 8. | ALA4838791 | F | Cytotoxicity against human U-87MG cells assessed as cell growth inhibition by measuring maximum efficacy measured after 48 hrs by MTS colorimetric assay relative to control | Homo sapiens | 2 | ALA4837226 | cell-based format | Scientific Literature | |
| 9. | ALA4838792 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor volume at 25 mg/kg, ip administered every 2 days for 35 days | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 10. | ALA4838793 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor weight at 25 mg/kg, ip administered every 2 days for 35 days | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 11. | ALA4838794 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in glioma tumors at 25 mg/kg, ip administered every 2 days for 35 days by hematoxylin and eosin staining based assay | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 12. | ALA4838795 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in Ki67 expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 13. | ALA4838796 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in CD31 marker expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 14. | ALA4838797 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in Bcl2 protein expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 15. | ALA4838798 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in GFAP expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 16. | ALA4838799 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as reduction in CD133 marker expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 17. | ALA4838800 | F | Antitumor activity against human U-87MG cells xenografted in BALB/c nu/nu mouse assessed as increase in activated caspase-3 expression at 25 mg/kg, ip administered every 2 days for 35 days by DAPI staining based immunofluorescence analysis | Homo sapiens | 1 | ALA4837226 | organism-based format | Scientific Literature | |
| 18. | ALA4838801 | F | Cytotoxicity against Bcr-Abl expressing human KU812 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 4 | ALA4837226 | cell-based format | Scientific Literature | |
| 19. | ALA4838802 | F | Cytotoxicity against Imatinib mesylate sensitive wild-type human KBM5 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 4 | ALA4837226 | cell-based format | Scientific Literature | |
| 20. | ALA4838803 | F | Cytotoxicity against imatinib mesylate resistant wild-type human KBM5 cells expressing T315I mutant assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 4 | ALA4837226 | cell-based format | Scientific Literature |
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