# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4840847 | Binding | Inhibition of mPGES-1 obtained from IL-beta stimulated human A549 cells microsomes assessed as residual activity by measuring conversion of PGH2 to PGE2 at 10 uM by cell-free RP-HPLC method | Homo sapiens | 11 | ALA4840316 | microsome format | Scientific Literature | |
2. | ALA4840849 | Binding | Inhibition of 5-LO in A23187-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation by measuring residual activity at 10 uM measured after 20 mins by RP-HPLC method | Homo sapiens | 11 | ALA4840316 | tissue-based format | Scientific Literature | |
3. | ALA4840850 | Binding | Inhibition of 5-LO in A23187/AA-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation by measuring residual activity at 10 uM measured after 20 mins by RP-HPLC method | Homo sapiens | 11 | ALA4840316 | tissue-based format | Scientific Literature |