| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4824798 | F | Antiproliferative activity against human NCI-H2228 cells assessed as inhibition of cell proliferation measured by CCK8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA4824799 | F | Antiproliferative activity against mouse BaF3 cells overexpressing ALK assessed as inhibition of cell proliferation measured by CCK8 assay | Mus musculus | 18 | cell-based format | Scientific Literature | ||
| 3. | ALA4824800 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G1 phase at 20 nM measured after 12 hrs by PI staining based flow cytometry method (Rvb = 67.77%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4824801 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in S phase at 20 nM measured after 12 hrs by PI staining based flow cytometry method (Rvb = 30%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4824802 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G2/M phase at 20 nM measured after 12 hrs by PI staining based flow cytometry method (Rvb = 2.23%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4824803 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G1 phase at 20 nM measured after 24 hrs by PI staining based flow cytometry method (Rvb = 67.77%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4824804 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in S phase at 20 nM measured after 24 hrs by PI staining based flow cytometry method (Rvb = 30%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4824805 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G2/M phase at 20 nM measured after 24 hrs by PI staining based flow cytometry method (Rvb = 2.23%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4824806 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G1 phase at 20 nM measured after 48 hrs by PI staining based flow cytometry method (Rvb = 67.77%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4824807 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in S phase at 20 nM measured after 48 hrs by PI staining based flow cytometry method (Rvb = 30%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4824808 | F | Cell cycle arrest in human NCI-H2228 cells assessed as accumulation of cells in G2/M phase at 20 nM measured after 48 hrs by PI staining based flow cytometry method (Rvb = 2.23%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4824809 | F | Cell cycle arrest in human NCI-H2228 cells assessed as downregulation of CDK4 protein expression at 20 nM measured after 12 to 48 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4824810 | F | Cell cycle arrest in human NCI-H2228 cells assessed as downregulation of Cyclin D1 protein expression at 20 nM measured after 12 to 48 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4824811 | F | Induction of apoptosis in human NCI-H2228 cells assessed as viable cells at 5 nM measured after 24 hrs by Annexin V-FITC.PI staining based flow cytometry assay (Rvb = 95.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4824812 | F | Induction of apoptosis in human NCI-H2228 cells assessed as early apoptotic cells at 5 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 2.18%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4824813 | F | Induction of apoptosis in human NCI-H2228 cells assessed as late apoptotic cells at 5 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 2.02%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4824814 | F | Induction of apoptosis in human NCI-H2228 cells assessed as necrotic cells at 5 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 0.21%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4824815 | F | Induction of apoptosis in human NCI-H2228 cells assessed as viable cells at 25 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 95.6%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4824816 | F | Induction of apoptosis in human NCI-H2228 cells assessed as early apoptotic cells at 25 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 2.18%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4824817 | F | Induction of apoptosis in human NCI-H2228 cells assessed as late apoptotic cells at 25 nM measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry assay (Rvb = 2.02%) | Homo sapiens | 2 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!