# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4810919 | F | Cytotoxicity against human U-87MG cells assessed as reduction in total cell count measured after 96 hrs by Hoechst staining analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4810920 | F | Cytotoxicity against human U-87MG cells assessed as reduction in total cell count measured after 96 hrs in presence of TMZ by Hoechst staining analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4810921 | F | Antiproliferative activity against human U-87MG cells assessed as reduction in cell proliferation measured after 48 hrs by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4810922 | F | Antiproliferative activity against human U-87MG cells assessed as reduction in cell proliferation measured after 48 hrs in presence of TMZ by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4810923 | F | Cytotoxicity against patient derived human GBM cells assessed as reduction in total cell count measured after 96 hrs by Hoechst staining analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4810924 | F | Cytotoxicity against patient derived human GBM cells assessed as reduction in total cell count measured after 96 hrs in presence of TMZ by Hoechst staining analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4810925 | F | Antiproliferative activity against patient derived human GBM cells assessed as reduction in cell proliferation measured after 48 hrs by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4810926 | F | Antiproliferative activity against patient derived human GBM cells assessed as reduction in cell proliferation measured after 48 hrs in presence of TMZ by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4810927 | A | Drug uptake in human U-87MG cells assessed as increase in fluorescence intensity of far red signal at 10 uM preincubated with HIF-1alpha stabilizer, 3,4-DHB followed by incubation with drug for 1 hr by fluorescence imaging analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4810928 | A | Drug uptake in patient-derived human GBM cells assessed as increase in fluorescence intensity of far red signal at 10 uM preincubated with HIF-1alpha stabilizer, 3,4-DHB followed by incubation with drug for 1 hr by fluorescence imaging analysis | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
11. | ALA4810929 | F | Cytotoxicity against human KNS-42 cells assessed as reduction in total cell count measured after 96 hrs by Hoechst staining analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4810930 | F | Cytotoxicity against human KNS-42 cells assessed as reduction in total cell count measured after 96 hrs in presence of TMZ by Hoechst staining based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4810931 | F | Antiproliferative activity against human KNS-42 cells assessed as reduction in cell proliferation measured after 48 hrs by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4810932 | F | Antiproliferative activity against human KNS-42 cells assessed as reduction in cell proliferation measured after 48 hrs in presence of TMZ by EdU-incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4810933 | F | Induction of apoptosis in patient derived human GBM cells assessed as increase in cleaved caspase-3 positive cells at IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4810934 | A | Cytotoxicity against primary brain pericytes (unknown origin) | Not specified | 1 | cell-based format | Scientific Literature | ||
17. | ALA4810935 | U | Selectivity ratio of EC50 for cytotoxicity against primary brain pericytes (unknown origin) to EC50 for cytotoxicity against patient derived human GBM cells | 1 | cell-based format | Scientific Literature | |||
18. | ALA4810936 | F | Synergistic cytotoxicity against patient derived human GBM cells assessed as combination index at 0.04 nM measured after 96 hrs in presence of TMZ by Hoechst staining based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4810937 | F | Synergistic cytotoxicity against patient derived human GBM cells assessed as combination index at 0.2 nM measured after 96 hrs in presence of TMZ by Hoechst staining based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4810938 | F | Synergistic cytotoxicity against patient derived human GBM cells assessed as combination index at 1 nM measured after 96 hrs in presence of TMZ by Hoechst staining based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |