#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4824242	Binding	Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate by spectrophotometric assay	Leishmania infantum	29	ALA4823264	assay format	Scientific Literature
2.	ALA4824244	Binding	Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR dimer using TS2 as substrate after 16 hrs by ELISA	Leishmania infantum	27	ALA4823264	assay format	Scientific Literature
3.	ALA4824261	Functional	Antileishmanial activity against promastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells incubated for 24 hrs by propidium iodide staining based flow cytometry	Leishmania infantum	23	ALA4823264	organism-based format	Scientific Literature
4.	ALA4824262	Functional	Antileishmanial activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells incubated for 24 hrs by propidium iodide staining based flow cytometry	Leishmania infantum	23	ALA4823264	organism-based format	Scientific Literature
5.	ALA4824263	ADME	Cytotoxicity against human HepG2 cells incubated for 24 hrs by crystal violet staining based assay	Homo sapiens	23	ALA4823264	cell-based format	Scientific Literature
6.	ALA4824264	Toxicity	Selectivity index, ratio of EC50 for human HepG2 cells to EC50 for promastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells		23	ALA4823264	cell-based format	Scientific Literature
7.	ALA4824265	Toxicity	Selectivity index, ratio of EC50 for human HepG2 cells to EC50 for axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human HepG2 cells		23	ALA4823264	cell-based format	Scientific Literature
8.	ALA4824266	Functional	Leishmanicidal activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells assessed as reduction in intracellular amastigotes incubated for 24 hrs by propidium iodide staining based flow cytometry	Leishmania infantum	13	ALA4823264	organism-based format	Scientific Literature
9.	ALA4824267	ADME	Cytotoxicity against human THP-1 cells by LDH assay	Homo sapiens	13	ALA4823264	cell-based format	Scientific Literature
10.	ALA4824268	ADME	Cytotoxicity against human THP-1 cells at 75 uM by LDH assay	Homo sapiens	4	ALA4823264	cell-based format	Scientific Literature