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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4841644 ADME Inhibition of CYP3A4T in human liver microsomes using midazolam as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 2 ALA4840351 microsome format Scientific Literature 2. ALA4841645 ADME Inhibition of CYP3A4M in human liver microsomes using midazolam as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 2 ALA4840351 microsome format Scientific Literature 3. ALA4841646 ADME Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 2 ALA4840351 microsome format Scientific Literature 4. ALA4841647 ADME Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 2 ALA4840351 microsome format Scientific Literature 5. ALA4841648 ADME Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 2 ALA4840351 microsome format Scientific Literature 6. ALA4841649 ADME Cmax in ICR mouse at 15 mg/kg, po after 24 hrs Mus musculus 2 ALA4840351 organism-based format Scientific Literature 7. ALA4841650 Functional Receptor occupancy at BTK in PBMC of ICR mouse at 15 mg/kg, po after 24 hrs by ELISA Mus musculus 1 ALA4840351 organism-based format Scientific Literature 8. ALA4841651 Functional Receptor occupancy at BTK in spleen of ICR mouse at 15 mg/kg, po after 24 hrs by ELISA Mus musculus 2 ALA4840351 organism-based format Scientific Literature 9. ALA4841652 ADME Drug concentration in ICR mouse plasma at 15 mg/kg, po after 2 hrs Mus musculus 1 ALA4840351 organism-based format Scientific Literature 10. ALA4841653 Functional Receptor occupancy at BTK in PBMC of ICR mouse at 15 mg/kg, po after 1 hr by ELISA Mus musculus 1 ALA4840351 organism-based format Scientific Literature 11. ALA4841654 Functional Receptor occupancy at BTK in spleen of ICR mouse at 15 mg/kg, po after 1 hr by ELISA Mus musculus 1 ALA4840351 organism-based format Scientific Literature 12. ALA4841655 Toxicity Toxicity in SFP CD-1 mouse assessed as pathological change in visceral organs at 10 to 1280 mg/kg, po administered for 7 days by H and E staining based assay Mus musculus 1 ALA4840351 organism-based format Scientific Literature 13. ALA4841656 Toxicity Toxicity in SFP CD-1 mouse assessed as change in temperature at 10 to 1280 mg/kg, po administered for 7 days Mus musculus 1 ALA4840351 organism-based format Scientific Literature 14. ALA4841657 Toxicity Toxicity in SFP CD-1 mouse assessed as change in animal color at 10 to 1280 mg/kg, po administered for 7 days Mus musculus 1 ALA4840351 organism-based format Scientific Literature 15. ALA4841658 Toxicity Toxicity in SFP CD-1 mouse assessed as change in behavior at 10 to 1280 mg/kg, po administered for 7 days Mus musculus 1 ALA4840351 organism-based format Scientific Literature 16. ALA4841659 Toxicity Toxicity in SFP CD-1 mouse assessed as change in body weight at 10 to 1280 mg/kg, po administered for 7 days Mus musculus 1 ALA4840351 organism-based format Scientific Literature 17. ALA4841660 Toxicity Toxicity in SFP CD-1 mouse assessed as mortality at 10 to 1280 mg/kg, po administered for 7 days Mus musculus 1 ALA4840351 organism-based format Scientific Literature 18. ALA4841661 ADME Oral bioavailability in Sprague-Dawley rat at 5 mg/kg measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA4840351 organism-based format Scientific Literature 19. ALA4841662 ADME AUC in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA4840351 organism-based format Scientific Literature 20. ALA4841663 ADME Cmax in Sprague-Dawley rat at 5 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis Rattus norvegicus 1 ALA4840351 organism-based format Scientific Literature