# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4842830 | Functional | Antifungal activity against fluconazole-resistant Candida tropicalis 5008 assessed as inhibition of fungal growth incubated for 48 hrs by two-fold serial microdilution method | Candida tropicalis | 17 | ALA4842325 | organism-based format | Scientific Literature | |
2. | ALA4842831 | Functional | Antifungal activity against fluconazole-resistant Candida tropicalis 3890 assessed as inhibition of fungal growth incubated for 48 hrs by two-fold serial microdilution method | Candida tropicalis | 17 | ALA4842325 | organism-based format | Scientific Literature | |
3. | ALA4842832 | Functional | Antifungal activity against Cryptococcus neoformans H99 assessed as inhibition of fungal growth incubated for 72 hrs by two-fold serial microdilution method | Cryptococcus neoformans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
4. | ALA4842833 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans SC5314 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
5. | ALA4842834 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans 0304103 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
6. | ALA4842835 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans 7781 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
7. | ALA4842836 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans 4108 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
8. | ALA4842837 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans 10061 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
9. | ALA4842838 | Functional | Antifungal activity against fluconazole-sensitive Candida albicans 9770 assessed as inhibition of fungal growth | Candida albicans | 17 | ALA4842325 | organism-based format | Scientific Literature | |
10. | ALA4842839 | ADME | Cytotoxicity against human HUVEC assessed as reduction in cell viability | Homo sapiens | 1 | ALA4842325 | cell-based format | Scientific Literature | |
11. | ALA4842840 | Functional | Antifungal activity against fluconazole-resistant Candida tropicalis 5008 assessed as inhibition of cell proliferation at 8 ug/ml measured for 48 hrs by time growth curve assay | Candida tropicalis | 1 | ALA4842325 | organism-based format | Scientific Literature | |
12. | ALA4842841 | Functional | Antifungal activity against fluconazole-sensitive Cryptococcus neoformans H99 assessed as inhibition of cell proliferation at 2 to 8 ug/ml measured for 48 hrs by time growth curve assay | Cryptococcus neoformans | 2 | ALA4842325 | organism-based format | Scientific Literature | |
13. | ALA4842843 | Functional | Inhibition of biofilm formation in Candida tropicalis 5008 at 64 ug/ml incubated for 24 hrs by XTT reduction assay | Candida tropicalis | 1 | ALA4842325 | organism-based format | Scientific Literature | |
14. | ALA4842845 | Functional | Inhibition of biofilm formation in Cryptococcus neoformans H99 at 64 ug/ml incubated for 24 hrs by XTT reduction assay | Cryptococcus neoformans | 1 | ALA4842325 | organism-based format | Scientific Literature | |
15. | ALA4842846 | Functional | Inhibition of capsule formation in Cryptococcus neoformans H99 assessed as reduction in capsule size at 40 to 50 ug/ml incubated for 24 hrs by laser scanning confocal microscopic analysis | Cryptococcus neoformans | 1 | ALA4842325 | assay format | Scientific Literature | |
16. | ALA4842847 | Functional | Downregulation of CAP10 gene expression in Cryptococcus neoformans H99 at 2 ug/ml measured after 24 hrs by qRT-PCR analysis | Cryptococcus neoformans | 2 | ALA4842325 | assay format | Scientific Literature | |
17. | ALA4842848 | Functional | Downregulation of CAP60 gene expression in Cryptococcus neoformans H99 at 2 ug/ml measured after 24 hrs by qRT-PCR analysis | Cryptococcus neoformans | 1 | ALA4842325 | assay format | Scientific Literature | |
18. | ALA4842849 | Functional | Downregulation of CAP59 gene expression in Cryptococcus neoformans H99 at 2 ug/ml measured after 24 hrs by qRT-PCR analysis | Cryptococcus neoformans | 2 | ALA4842325 | assay format | Scientific Literature | |
19. | ALA4842850 | Binding | Inhibition of CYP51 in Candida tropicalis 5008 assessed as ergosterol level at 4 ug/ml by GC-MS analysis (Rvb = 84.91%) | Candida tropicalis | 1 | ALA4842325 | assay format | Scientific Literature | |
20. | ALA4842851 | Binding | Inhibition of CYP51 in Candida tropicalis 5008 assessed as unknown sterol level at 4 ug/ml by GC-MS analysis (Rvb = 6.48%) | Candida tropicalis | 1 | ALA4842325 | assay format | Scientific Literature |