# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4816179 | B | Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrate | Homo sapiens | 4 | ALA4813974 | subcellular format | Scientific Literature | |
2. | ALA4816187 | B | Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at 1:1 substrate to compound molar ratio at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 2 | ALA4813974 | subcellular format | Scientific Literature | |
3. | ALA4816188 | B | Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at 5 uM at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 2 | ALA4813974 | subcellular format | Scientific Literature | |
4. | ALA4816189 | B | Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at 20:1 substrate to compound molar ratio at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 2 | ALA4813974 | subcellular format | Scientific Literature | |
5. | ALA4816191 | B | Inhibition of human ASAH2 stably over expressed in human HT-29 cell lysate using RBM14C24 fluorogenic substrate measured at pH 7.5 by fluorescence spectrophotometry | Homo sapiens | 4 | ALA4813974 | subcellular format | Scientific Literature | |
6. | ALA4816195 | B | Inhibition of ASAH2 in wild type mouse intact embryonic fibroblast using RBM14C16 fluorogenic substrate measured at pH 7.5 incubated for 3 hrs by fluorescence spectrophotometry | Mus musculus | 4 | ALA4813974 | tissue-based format | Scientific Literature | |
7. | ALA4816196 | B | Inhibition of ACER3 in ASAH2-null mouse intact embryonic fibroblast using RBM14C16 fluorogenic substrate measured at pH 9 for 3 hrs by fluorescence spectrophotometry | Mus musculus | 4 | ALA4813974 | tissue-based format | Scientific Literature |