#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4809275	Binding	Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay	Rattus norvegicus	40	ALA4808182	cell-based format	Scientific Literature
2.	ALA4809276	Binding	Activation of recombinant rat sGC alpha1 subunit expressed in CHO cells assessed as induction of [32P-cGMP] formation by measuring efficacy using alpha-[32P-GTP] as substrate measured after 6 mins by luminescence assay relative to control	Rattus norvegicus	15	ALA4808182	cell-based format	Scientific Literature
3.	ALA4809277	ADME	Clearance in Wistar rat at 0.3 mg/kg, iv measured up to 24 hrs by LC-MS analysis	Rattus norvegicus	7	ALA4808182	organism-based format	Scientific Literature
4.	ALA4809278	ADME	Plasma clearance in iv dosed Beagle dog measured up to 24 hrs by LC-MS analysis	Canis lupus familiaris	6	ALA4808182	organism-based format	Scientific Literature
5.	ALA4809279	ADME	Plasma clearance in iv dosed cynomolgus monkey measured up to 24 hrs by LC-MS analysis	Macaca fascicularis	6	ALA4808182	organism-based format	Scientific Literature
6.	ALA4809280	Binding	Activation of recombinant rat sGC expressed in CHO cells by luminescence assay	Rattus norvegicus	8	ALA4808182	cell-based format	Scientific Literature
7.	ALA4809283	ADME	Volume of distribution at steady state in iv dosed Wistar rat measured up to 24 hrs by LC-MS analysis	Rattus norvegicus	2	ALA4808182	organism-based format	Scientific Literature
8.	ALA4809284	ADME	Half life in iv dosed Wistar rat measured up to 24 hrs by LC-MS analysis	Rattus norvegicus	2	ALA4808182	organism-based format	Scientific Literature
9.	ALA4809285	ADME	Oral bioavailability in Wistar rat measured up to 24 hrs by LC-MS analysis	Rattus norvegicus	2	ALA4808182	organism-based format	Scientific Literature
10.	ALA4809286	ADME	Volume of distribution at steady state in iv dosed Beagle dog measured up to 24 hrs by LC-MS analysis	Canis lupus familiaris	2	ALA4808182	organism-based format	Scientific Literature
11.	ALA4809287	ADME	Half life in iv dosed Beagle dog measured up to 24 hrs by LC-MS analysis	Canis lupus familiaris	2	ALA4808182	organism-based format	Scientific Literature
12.	ALA4809288	ADME	Oral bioavailability in Beagle dog measured up to 24 hrs by LC-MS analysis	Canis lupus familiaris	2	ALA4808182	organism-based format	Scientific Literature
13.	ALA4809289	ADME	Volume of distribution at steady state in iv dosed cynomolgus monkey measured up to 24 hrs by LC-MS analysis	Macaca fascicularis	1	ALA4808182	organism-based format	Scientific Literature
14.	ALA4809290	ADME	Half life in iv dosed cynomolgus monkey measured up to 24 hrs by LC-MS analysis	Macaca fascicularis	1	ALA4808182	organism-based format	Scientific Literature
15.	ALA4809291	ADME	Oral bioavailability in cynomolgus monkey measured up to 24 hrs by LC-MS analysis	Macaca fascicularis	1	ALA4808182	organism-based format	Scientific Literature
16.	ALA4809292	ADME	Induction of CYP1A2 in human hepatocytes at > 123 ng/ml using phenacetin as substrate incubated for 60 mins by LC-MS/MS analysis	Homo sapiens	1	ALA4808182	cell-based format	Scientific Literature
17.	ALA4809295	ADME	Induction of CYP3A4 in human hepatocytes using phenacetin as substrate incubated for 60 mins by LC-MS/MS analysis	Homo sapiens	6	ALA4808182	cell-based format	Scientific Literature