# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4830651 | Binding | Inhibition of capsid protein in HBV infected in human HepDES19 cells assessed as inhibition of viral replication incubated for 3 days by strand preferential qPCR analysis | Hepatitis B virus | 15 | ALA4828746 | cell-based format | Scientific Literature | |
2. | ALA4830654 | ADME | Cytotoxicity against human HepDES19 cells assessed as reduction in cell viability measured after 3 days by by MTS assay | Homo sapiens | 15 | ALA4828746 | cell-based format | Scientific Literature | |
3. | ALA4830655 | Toxicity | Selectivity index, ratio of CC50 for human HepDES19 cells to EC50 for inhibition of capsid protein-mediated antiviral activity against HBV infected in human HepDES19 cells assessed as inhibition of DNA replication | 15 | ALA4828746 | cell-based format | Scientific Literature | ||
4. | ALA4830656 | Binding | Inhibition of capsid protein in HBV infected in human HepDES19 cells assessed as inhibition of viral replication by measuring plus polarity DNA level at 10 uM incubated for 3 days by strand preferential qPCR analysis relative to control | Hepatitis B virus | 3 | ALA4828746 | cell-based format | Scientific Literature | |
5. | ALA4830657 | Binding | Inhibition of capsid protein in HBV infected in human HepDES19 cells assessed as inhibition of viral replication by measuring plus polarity DNA level at 3 uM incubated for 3 days by strand preferential qPCR analysis relative to control | Hepatitis B virus | 3 | ALA4828746 | cell-based format | Scientific Literature | |
6. | ALA4830660 | Binding | Inhibition of capsid protein in HBV infected in human HepDES19 cells assessed as inhibition of viral replication by measuring minus polarity DNA level at 10 uM incubated for 3 days by strand preferential qPCR analysis relative to control | Hepatitis B virus | 3 | ALA4828746 | cell-based format | Scientific Literature | |
7. | ALA4830661 | Binding | Inhibition of capsid protein in HBV infected in human HepDES19 cells assessed as inhibition of viral replication by measuring minus polarity DNA level at 3 uM incubated for 3 days by strand preferential qPCR analysis relative to control | Hepatitis B virus | 3 | ALA4828746 | cell-based format | Scientific Literature |