| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4816089 | F | Induction of apoptosis in human A-431 cells assessed as chromatin condensation at 7.5 to 30 nM incubated for 48 hrs by Hoechst33342 staining based fluorescent microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4816090 | F | Induction of apoptosis in human A-431 cells assessed as nuclear fragmentation at 7.5 to 30 nM incubated for 48 hrs by Hoechst33342 staining based fluorescent microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4816091 | F | Induction of mitochondria membrane potential loss in human A-431 cells assessed as red fluorescence intensity at 7.5 nM incubated 48 hrs by JC-1 probe based flow cytometry analysis (Rvb = 93.83%) | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 4. | ALA4816092 | F | Induction of apoptosis in human A-431 cells assessed as activation of p53 at 7.5 to 30 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4816093 | F | Induction of mitochondria membrane potential loss in human A-431 cells assessed as red fluorescence intensity at 15 nM incubated 48 hrs by JC-1 probe based flow cytometry analysis (Rvb = 93.83%) | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 6. | ALA4816094 | F | Induction of mitochondria membrane potential loss in human A-431 cells assessed as green fluorescence intensity at 15 nM incubated 48 hrs by JC-1 probe based flow cytometry analysis (Rvb = 5.98%) | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 7. | ALA4816095 | F | Antiproliferative activity against human A-431 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
| 8. | ALA4816096 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 9. | ALA4816097 | F | Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 10. | ALA4816098 | F | Antiproliferative activity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 11. | ALA4816099 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 12. | ALA4816100 | F | Antiproliferative activity against mouse H22 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Mus musculus | 13 | cell-based format | Scientific Literature | ||
| 13. | ALA4816101 | A | Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 14. | ALA4816102 | F | Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4816103 | F | Antiproliferative activity against ADR-resistant human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA4816104 | F | Resistant index, ratio of IC50 for ADR-resistant human Bel-7402 cells to IC50 for human Bel-7402 cells | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 17. | ALA4816105 | F | Antiproliferative activity against taxol-resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA4816106 | F | Resistant index, ratio of IC50 for taxol-resistant human HCT-8 cells to IC50 for human HCT-8 cells | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 19. | ALA4816107 | F | Antiproliferative activity against VCR resistant human K562/VCR cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA4816108 | F | Resistant index, ratio of IC50 for VCR resistant human K562 cells to IC50 for human K562 cells | Homo sapiens | 3 | assay format | Scientific Literature |
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