| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4832253 | F | Growth inhibition of human panel NCI-60 (60 carcinoma cells) assessed as growth percent at 10 uM measured after 48 hrs by SRB assay relative to control | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 2. | ALA4832283 | B | Inhibition of ErbB4 (unknown origin) at 10 uM incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA4832291 | B | Inhibition of ErbB4 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 4. | ALA4832299 | B | Inhibition of wild type B-RAF (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4832300 | B | Inhibition of A-RAF (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4832301 | B | Inhibition of EGFR- L861Q mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4832302 | B | Inhibition of EGFR- T790M mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4832303 | B | Inhibition of EGFR T790M/L858R mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4832304 | B | Inhibition of FLT-3(unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4832305 | B | Inhibition of MEK2 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4832306 | B | Selectivity ratio of IC50 for inhibition of EFGR-T790M mutant (unknown origin) to IC50 for ErbB4 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4832310 | B | Inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4832311 | B | Safety index, ratio of test compound IC50 to E-4031 IC50 for inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA4832312 | A | Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrate incubated for 20 mins by fluorescence based analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4832313 | A | Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrate incubated for 20 mins by fluorescence based analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA4832314 | A | Potency index, ratio of test compound IC50 to ketoconazole IC50 for inhibition of CYP2D6 (unknown origin) using EOMCC as a substrate incubated for 20 mins by fluorescence based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA4832315 | A | Potency index, ratio of test compound IC50 to ketoconazole IC50 for inhibition of CYP3A4 (unknown origin) using BOMCC as a substrate incubated for 20 mins by fluorescence based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA4832316 | B | Inhibition of KDR (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4832317 | B | Inhibition of RAF1 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4832318 | B | Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting method | Homo sapiens | 3 | single protein format | Scientific Literature |
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