# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4834344 | B | Inhibition of APN in pig kidney microsomes assessed as reduction in p-nitroanilide release using L-leu-p-nitroanilide as substrate incubated for 30 mins by UV absorption based analysis | Sus scrofa | 20 | microsome format | Scientific Literature | ||
2. | ALA4834346 | B | Inhibition of AKT1 (unknown origin) at 1 uM incubated for 40 mins in presence of ATP by Kinase-Glo reagent based luminescence analysis relative to control | Homo sapiens | 17 | single protein format | Scientific Literature | ||
3. | ALA4834347 | B | Inhibition of AKT1 (unknown origin) at 200 nM incubated for 40 mins in presence of ATP by Kinase-Glo reagent based luminescence analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
4. | ALA4834348 | B | Inhibition of AKT1 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-Glo reagent based luminescence analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
5. | ALA4834349 | B | Inhibition of HDAC in human HeLa nuclear extract at 10 uM using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 4 | subcellular format | Scientific Literature | ||
6. | ALA4834350 | B | Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate at 10 uM preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA4834351 | B | Inhibition of HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate at 10 uM preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
8. | ALA4834352 | F | Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4834353 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA4834354 | F | Antiproliferative activity against human AGS cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4834355 | F | Anti-angiogenic activity against HUVEC cells assessed as inhibition of tubular structure formation at 10 uM incubated for 6 days by Matrigel based phase contrast microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |