# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4829376 | Binding | Inhibition of human 20S proteasome LMP2 using Ac-PAL-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assay | Homo sapiens | 20 | ALA4828720 | single protein format | Scientific Literature | |
2. | ALA4829377 | Binding | Inhibition of human 20S proteasome Y using Ac-nLPnLD-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assay | Homo sapiens | 20 | ALA4828720 | assay format | Scientific Literature | |
3. | ALA4829378 | Binding | Inhibition of human 20S proteasome LMP7 using Ac-ANW-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assay | Homo sapiens | 20 | ALA4828720 | single protein format | Scientific Literature | |
4. | ALA4829379 | Binding | Inhibition of human 20S proteasome X using Ac-WLA-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assay | Homo sapiens | 20 | ALA4828720 | assay format | Scientific Literature | |
5. | ALA4829383 | Binding | Inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells using Ac-PAL-AMC as fluorogenic substrate incubated for 72 hrs by fluorescence assay | Homo sapiens | 7 | ALA4828720 | cell-based format | Scientific Literature | |
6. | ALA4829384 | Binding | Inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells overexpressing ABCB1 using Ac-PAL-AMC as fluorogenic substrate incubated for 72 hrs by fluorescence assay | Homo sapiens | 7 | ALA4828720 | cell-based format | Scientific Literature | |
7. | ALA4829385 | Binding | Selectivity index, ratio of IC50 for inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells overexpressing ABCB1 to IC50 for inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells | Homo sapiens | 5 | ALA4828720 | cell-based format | Scientific Literature |