# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4810079 | B | Inhibition of human recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 22 to 24 hrs by RapidFire Mass spectroscopy | Homo sapiens | 27 | ALA4808207 | single protein format | Scientific Literature | |
2. | ALA4810080 | B | Inhibition of mouse recombinant NNMT using nicotinamide and SAM as substrate assessed as reduction in 1-methyl-nicotinamide formation incubated for 22 to 24 hrs by RapidFire Mass spectroscopy | Mus musculus | 27 | ALA4808207 | single protein format | Scientific Literature | |
3. | ALA4810081 | B | Inhibition of human NNMT expressed in HEK293 cells assessed as reduction in 1-methyl-nicotinamide formation measured after 24 hrs by RapidFire Mass spectroscopy | Homo sapiens | 4 | ALA4808207 | cell-based format | Scientific Literature | |
4. | ALA4810082 | A | Cytotoxicity against human HEK293 cells overexpressing human NNMT assessed as reduction in ATP level measured after 24 hrs by CellTiter-glo luminescence assay | Homo sapiens | 4 | ALA4808207 | cell-based format | Scientific Literature |