| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4838837 | B | Inhibition of Influenza A virus (A/Anhui/1/2005(H5N1) Neuraminidase using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/Anhui/1/2005(H5N1)) | 25 | single protein format | Scientific Literature | ||
| 2. | ALA4838838 | B | Inhibition of Influenza A virus (A/California/04/2009(H1N1)) Neuraminidase using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/California/04/2009(H1N1)) | 5 | single protein format | Scientific Literature | ||
| 3. | ALA4838839 | B | Inhibition of Influenza A virus (A/Anhui/1/2005(H5N1) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/Anhui/1/2005(H5N1)) | 6 | assay format | Scientific Literature | ||
| 4. | ALA4838840 | B | Inhibition of Influenza A virus (A/California/04/2009 (H1N1)) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/California/04/2009(H1N1)) | 6 | assay format | Scientific Literature | ||
| 5. | ALA4838841 | F | Antiviral activity against Influenza A virus (A/California/07/09(H1N1)) infected in MDCK cells assessed as reduction in viral titer incubated for 2 days by crystal violet staining based plaque reduction assay | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA4838842 | F | Antiviral activity against Influenza A virus (A/California/07/09(H1N1)) infected in MDCK cells assessed as reduction in viral titer measured after 46 hrs by crystal violet staining based plaque reduction assay | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4838843 | A | Cytotoxicity against MDCK cells assessed as reduction in cell viability at 250 uM | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4838844 | A | Metabolic stability in mouse liver microsome assessed as half life | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 9. | ALA4838845 | A | Metabolic stability in rat liver microsome assessed as half life | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 10. | ALA4838846 | A | Metabolic stability in human liver microsome assessed as half life | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 11. | ALA4838847 | A | Stability of the compound in human plasma assessed as parent compound remaining measured immediately | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 12. | ALA4838848 | A | Stability of the compound in human plasma assessed as parent compound remaining measured after 10 mins | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 13. | ALA4838849 | A | Stability of the compound in human plasma assessed as parent compound remaining measured after 30 mins | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 14. | ALA4838850 | A | Stability of the compound in human plasma assessed as parent compound remaining measured after 60 mins | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 15. | ALA4838851 | A | Stability of the compound in human plasma assessed as parent compound remaining measured after 120 mins | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 16. | ALA4838852 | B | Potency index, ratio of oseltamivir carboxylate IC50 to test compound IC50 for inhibition of Influenza A virus (A/Anhui/1/2005(H5N1) Neuraminidase using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/Anhui/1/2005(H5N1)) | 4 | single protein format | Scientific Literature | ||
| 17. | ALA4838853 | B | Potency index, ratio of oseltamivir carboxylate IC50 to test compound IC50 for inhibition of Influenza A virus (A/Anhui/1/2005(H5N1) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/Anhui/1/2005(H5N1)) | 5 | assay format | Scientific Literature | ||
| 18. | ALA4838854 | B | Potency index, ratio of oseltamivir carboxylate IC50 to test compound IC50 for inhibition of Influenza A virus (A/California/04/2009 (H1N1)) Neuraminidase H274Y mutant using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric method | Influenza A virus (A/California/04/2009(H1N1)) | 5 | assay format | Scientific Literature |
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