# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4833628 | Binding | Inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using C100-FLAG as substrate incubated for 2 hrs by sandwich ELISA | Homo sapiens | 23 | ALA4831543 | cell-based format | Scientific Literature | |
2. | ALA4833629 | Binding | Noncompetitive inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using varying level of C100-FLAG as substrate incubated for 2 hrs by double reciprocal plot analysis | Homo sapiens | 4 | ALA4831543 | cell-based format | Scientific Literature | |
3. | ALA4833630 | Binding | Inhibition of TSA-Bpa-Bt labelling of gamma secretase (unknown origin) expressed in HEK293 cells at 10 uM preincubated for 1.5 hrs followed by irradiation for 30 mins by Western blot analysis | Homo sapiens | 4 | ALA4831543 | cell-based format | Scientific Literature | |
4. | ALA4833631 | Binding | Inhibition of HPI-Bpa-Bt labelling of gamma secretase (unknown origin) expressed in HEK293 cells at 10 uM preincubated for 1.5 hrs followed by irradiation for 30 mins by Western blot analysis | Homo sapiens | 4 | ALA4831543 | cell-based format | Scientific Literature | |
5. | ALA4833632 | Binding | Competitive inhibition of TSA 1 binding to gamma secretase (unknown origin) | Homo sapiens | 2 | ALA4831543 | protein complex format | Scientific Literature | |
6. | ALA4833633 | Binding | Competitive inhibition of HPI 2 binding to gamma secretase (unknown origin) | Homo sapiens | 2 | ALA4831543 | protein complex format | Scientific Literature |