# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4806265 | Binding | Inhibition of casein kinase 1delta (unknown origin) | Homo sapiens | 11 | ALA4804285 | single protein format | Patent Bioactivity Data | |
2. | ALA4806266 | Binding | Inhibition of casein kinase 1epsilon (unknown origin) | Homo sapiens | 11 | ALA4804285 | single protein format | Patent Bioactivity Data | |
3. | ALA4806269 | Binding | Inhibition of serine 2 phosphorylation of Rbb1 of RNA polymerase II in human MDA-MB-231 cells by In-cell western analysis | Homo sapiens | 9 | ALA4804285 | cell-based format | Patent Bioactivity Data | |
4. | ALA4806270 | Functional | Growth inhibition of human U87 cells measured after 72 hrs by Cell-Titer Glo assay | Homo sapiens | 11 | ALA4804285 | cell-based format | Patent Bioactivity Data | |
5. | ALA4806271 | Functional | Growth inhibition of human MDA-MB-231 cells measured after 72 hrs by Cell-Titer Glo assay | Homo sapiens | 11 | ALA4804285 | cell-based format | Patent Bioactivity Data | |
6. | ALA4806272 | Physicochemical | Solubility in phosphate buffered saline at pH 7.4 | 7 | ALA4804285 | small-molecule physicochemical format | Patent Bioactivity Data | ||
7. | ALA4806273 | ADME | Stability in human liver microsomes | Homo sapiens | 8 | ALA4804285 | microsome format | Patent Bioactivity Data | |
8. | ALA4806274 | ADME | Stability in mouse liver microsomes | Mus musculus | 8 | ALA4804285 | microsome format | Patent Bioactivity Data | |
9. | ALA4806275 | ADME | Stability in rat liver microsomes | Rattus norvegicus | 8 | ALA4804285 | microsome format | Patent Bioactivity Data | |
10. | ALA4806276 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 7 | ALA4804285 | single protein format | Patent Bioactivity Data | |
11. | ALA4806277 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 7 | ALA4804285 | single protein format | Patent Bioactivity Data | |
12. | ALA4806278 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 7 | ALA4804285 | single protein format | Patent Bioactivity Data | |
13. | ALA4806279 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 7 | ALA4804285 | single protein format | Patent Bioactivity Data | |
14. | ALA4806280 | ADME | Half-life in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
15. | ALA4806281 | ADME | Tmax in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
16. | ALA4806282 | ADME | Cmax in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
17. | ALA4806283 | ADME | AUC (last) in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
18. | ALA4806284 | ADME | Observed AUC (infinity) in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
19. | ALA4806285 | ADME | AUC (extrapolated) in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data | |
20. | ALA4806286 | ADME | Observed clearance in mouse at 20 mg/kg, ip | Mus musculus | 3 | ALA4804285 | organism-based format | Patent Bioactivity Data |