| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4834536 | B | Antagonist activity at mouse PXR in presence of PCN by luciferase reporter assay | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 2. | ALA4834537 | A | Agonist activity at mouse PXR by luciferase reporter assay | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 3. | ALA4834538 | A | Cytotoxicity against human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter measured after 24 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4834539 | B | Displacement of BODIPY FL vindoline from GST-tagged human PXR LBD incubated for 60 mins by TR-FRET assay | Homo sapiens | 83 | single protein format | Scientific Literature | ||
| 5. | ALA4834540 | B | Displacement of BODIPY FL vindoline from GST-tagged human PXR LBD at 10 uM incubated for 60 mins by TR-FRET assay relative to control | Homo sapiens | 77 | single protein format | Scientific Literature | ||
| 6. | ALA4834541 | A | Agonist activity at human PXR expressed in HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter incubated for 24 hrs by luciferase reporter assay | Homo sapiens | 83 | cell-based format | Scientific Literature | ||
| 7. | ALA4834542 | A | Agonist activity at human PXR expressed in HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter at 10 uM incubated for 24 hrs by luciferase reporter assay relative to control | Homo sapiens | 66 | cell-based format | Scientific Literature | ||
| 8. | ALA4834543 | B | Inverse agonist activity at human PXR expressed in HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter incubated for 24 hrs by luciferase reporter assay | Homo sapiens | 83 | cell-based format | Scientific Literature | ||
| 9. | ALA4834545 | B | Antagonist activity at human PXR expressed in HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter incubated for 24 hrs in presence of 5 uM rifampicin by luciferase reporter assay | Homo sapiens | 83 | cell-based format | Scientific Literature | ||
| 10. | ALA4834546 | B | Inhibition of human PXR expressed in HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter at 10 uM incubated for 24 hrs in presence of 5 uM rifampicin by luciferase reporter assay relative to control | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 11. | ALA4834547 | B | Agonist activity at human CAR by luciferase reporter assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA4834548 | B | Agonist activity at human VDR expressed in HEK293T cells by luciferase reporter assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4834549 | B | Antagonist activity at human VDR expressed in HEK293T cells in presence of 1alpha,25-dihydroxyvitamin D3 by luciferase reporter assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4834550 | B | Agonist activity at human FXR expressed in HEK293T cells by luciferase reporter assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4834551 | B | Antagonist activity at human FXR expressed in HEK293T cells in presence of GW4064 by luciferase reporter assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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