# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4821854 | Binding | Inhibition of recombinant human PHD2 (181 to 426 residues) using DLDLEMLAPYIPMDDDFQL peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by Q-TOF mass spectrometric analysis | Homo sapiens | 18 | ALA4819086 | single protein format | Scientific Literature | |
2. | ALA4821856 | ADME | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 100 uM incubated for 24 hrs by MTT assay | Homo sapiens | 1 | ALA4819086 | cell-based format | Scientific Literature | |
3. | ALA4821857 | Functional | Neuroprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as reduction in rate of cell death pretreated for 2 hrs followed by H2O2 challenge by phase contrast microscopic analysis | Homo sapiens | 2 | ALA4819086 | cell-based format | Scientific Literature |